What are the key clinical signs that indicate a need for immediate imaging in a patient with suspected traumatic brain injury?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 22 August 2025Updated: 22 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Key clinical signs indicating the need for immediate CT imaging in a patient with suspected traumatic brain injury include:

  • A Glasgow Coma Scale (GCS) score of 12 or less on initial assessment in the emergency department.
  • A GCS score of less than 15 at 2 hours after the injury.
  • Suspected open or depressed skull fracture.
  • Any sign of basal skull fracture such as haemotympanum, 'panda' eyes, cerebrospinal fluid leakage from the ear or nose, or Battle's sign.
  • Post-traumatic seizure.
  • Focal neurological deficit.
  • More than one episode of vomiting.

For patients who have had some loss of consciousness or amnesia since the injury, additional risk factors prompting imaging within 8 hours include:

  • Age 65 or over.
  • Any current bleeding or clotting disorders.
  • Dangerous mechanism of injury (e.g., pedestrian or cyclist struck by a motor vehicle, occupant ejected from a motor vehicle, or fall from height greater than 1 meter or 5 stairs).
  • More than 30 minutes of retrograde amnesia immediately before the injury.

In children under 16, immediate imaging is indicated with:

  • Suspicion of non-accidental injury.
  • Post-traumatic seizure.
  • GCS score less than 14 on initial assessment (or less than 15 for babies under 1 year).
  • GCS score less than 15 at 2 hours after injury.
  • Suspected open or depressed skull fracture or tense fontanelle.
  • Any sign of basal skull fracture.
  • Focal neurological deficit.
  • For babies under 1 year, a bruise, swelling, or laceration of more than 5 cm on the head.

These signs warrant a CT head scan within 1 hour of identification to detect clinically important traumatic brain injury and guide further management .

Educational content only. Always verify information and use clinical judgement.