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What are the key clinical features that suggest a diagnosis of urethral stricture in a male patient?
Answer
Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 22 August 2025
Key clinical features suggesting a diagnosis of urethral stricture in a male patient include:
- Lower urinary tract symptoms (LUTS): These commonly manifest as a weak or decreased urinary stream, hesitancy, straining to void, and a sensation of incomplete bladder emptying 1.
- Spraying or deviation of the urinary stream: This occurs due to narrowing of the urethral lumen causing turbulent flow (Barbagli et al., 2004).
- Recurrent urinary tract infections (UTIs): Strictures can cause urinary stasis, predisposing to infections 1.
- Urinary retention or difficulty initiating urination: Patients may report episodes of acute urinary retention or difficulty starting to pass urine 1.
- Perineal or penile pain or discomfort: Some patients experience pain along the urethra or perineum, which may be chronic or intermittent (Delavierre et al., 2010).
- History of urethral trauma, instrumentation, or infection: Previous catheterisation, urethritis, or trauma are important historical clues (Zhivov et al., 2017).
- Palpable induration or fibrosis along the penile or perineal urethra: On physical examination, a firm or fibrotic segment may be felt, especially in cases related to lichen sclerosus (Barbagli et al., 2004).
These features together raise clinical suspicion for urethral stricture and warrant further diagnostic evaluation such as uroflowmetry, urethrography, or cystoscopy [1, Zhivov et al., 2017].
Key References
- CG97 - Lower urinary tract symptoms in men: management
- NG12 - Suspected cancer: recognition and referral
- (Barbagli et al., 2004): Lichen sclerosus of the male genitalia and urethral stricture diseases.
- (Delavierre et al., 2010): [Symptomatic approach to chronic urethral pain].
- (Zhivov et al., 2017): [American urological association guideline for diagnosis and management of male urethral stricture 2016].
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