What are the recommended diagnostic tests for confirming Trichomonas vaginalis infection in symptomatic patients?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 22 August 2025Updated: 22 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

For symptomatic patients, the recommended diagnostic tests for confirming Trichomonas vaginalis infection primarily include Nucleic Acid Amplification Tests (NAATs) . NAATs are considered the most sensitive and specific method for detecting T. vaginalis . While wet mount microscopy can be performed, its sensitivity is significantly lower than NAATs, especially when parasite loads are low . Culture is also an available diagnostic option, but it is less frequently used for routine diagnosis due to its longer turnaround time . The use of highly accurate and efficient diagnostic methods, such as NAATs, is consistent with UK guidelines aimed at reducing sexually transmitted infections . These advanced tests help ensure accurate diagnosis and appropriate management for symptomatic individuals .

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