What are the recommended emergency management strategies for a patient presenting with CRAO?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 17 August 2025Updated: 17 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Central Retinal Artery Occlusion (CRAO) is considered a medical emergency requiring urgent management to prevent permanent visual loss , ().

Immediate Actions and Referral:

  • Arrange an urgent (same day) assessment by an ophthalmologist .
  • Consider Giant Cell Arteritis (GCA) as a potential underlying cause, especially if there is new visual loss (transient or permanent) or double vision .
  • If GCA is strongly suspected, immediate treatment with high-dose glucocorticoids is necessary . A specialist may advise a one-off high-dose corticosteroid treatment in primary care while the patient awaits transfer to ophthalmology . For acute or intermittent visual loss due to GCA, intravenous glucocorticoid therapy is usually given; if not possible, 60–100 mg oral prednisolone may be administered for up to 3 consecutive days .

Emergency Interventions (typically in secondary care):

  • Strategies aim to restore retinal blood flow and may include ocular massage, anterior chamber paracentesis, and the administration of vasodilators ().
  • Intravenous thrombolysis may be considered in selected cases, particularly within a narrow time window from the onset of symptoms (, ).
  • Antithrombotic therapy may also be used in the management of retinal artery occlusion ().

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