Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX
Central Retinal Artery Occlusion (CRAO) is considered a medical emergency requiring urgent management to prevent permanent visual loss NICE CKS, (Mac Grory et al. 2021).
Immediate Actions and Referral:
- Arrange an urgent (same day) assessment by an ophthalmologist NICE CKS.
- Consider Giant Cell Arteritis (GCA) as a potential underlying cause, especially if there is new visual loss (transient or permanent) or double vision NICE CKS.
- If GCA is strongly suspected, immediate treatment with high-dose glucocorticoids is necessary NICE CKS. A specialist may advise a one-off high-dose corticosteroid treatment in primary care while the patient awaits transfer to ophthalmology NICE CKS. For acute or intermittent visual loss due to GCA, intravenous glucocorticoid therapy is usually given; if not possible, 60–100 mg oral prednisolone may be administered for up to 3 consecutive days NICE CKS.
Emergency Interventions (typically in secondary care):
- Strategies aim to restore retinal blood flow and may include ocular massage, anterior chamber paracentesis, and the administration of vasodilators (Roskal-Wałek et al. 2024).
- Intravenous thrombolysis may be considered in selected cases, particularly within a narrow time window from the onset of symptoms (Mac Grory et al. 2021, Roskal-Wałek et al. 2024).
- Antithrombotic therapy may also be used in the management of retinal artery occlusion (Liu et al. 2025).
Key References
- CKS - Macular degeneration - age-related
- CKS - Age-related macular degeneration
- CKS - Glaucoma
- CKS - Giant cell arteritis
- NG82 - Age-related macular degeneration
- NG242 - Diabetic retinopathy: management and monitoring
- NG81 - Glaucoma: diagnosis and management
- (Mac Grory et al., 2021): Management of Central Retinal Artery Occlusion: A Scientific Statement From the American Heart Association.
- (Roskal-Wałek et al., 2024): Therapeutic Strategies for Retinal Artery Occlusion-A Literature Review.
- (Liu et al., 2025): Antithrombotic use in retinal artery occlusion: A narrative review.