What are the indications for referring a patient with ascites to secondary care for further management?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 17 August 2025Updated: 17 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Referral to secondary care for a patient with ascites is indicated in several situations:

  • Decompensated Liver Disease: If a person has signs of decompensated liver disease, which includes ascites, arrange emergency hospital admission or immediate referral to a hepatologist or gastroenterologist with an interest in hepatology . An urgent specialist nurse-led liver clinic may also be appropriate to avoid admission, depending on the patient's presentation, care plan, and local service provision .
  • Refractory Ascites: For people with cirrhosis who have refractory ascites, a Transjugular Intrahepatic Portosystemic Shunt (TIPS) procedure may be considered . Nurse-led day case paracentesis services for refractory ascites can also reduce emergency hospital admissions .
  • High Risk of Spontaneous Bacterial Peritonitis (SBP): Specialist treatment with prophylactic antibiotics may be considered if a person has ascites and is considered at high risk of infection, or if the consequences of infection could severely impact their outcome and care .
  • Suspected Ovarian Cancer: In women, if physical examination identifies ascites and/or a pelvic or abdominal mass (which is not obviously uterine fibroids), refer the woman using a suspected cancer pathway referral ,.

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