When should I consider referring a patient with trigeminal neuralgia for surgical evaluation?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 16 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Consider referring a patient with trigeminal neuralgia for surgical evaluation if their unilateral facial pain is refractory to treatment, particularly when initial pharmacological management with carbamazepine is not effective, not tolerated, or contraindicated. This referral should be made in line with the NICE guideline on neuropathic pain in adults and may involve seeking expert advice from a specialist pain service or a condition-specific service.

Additionally, adults presenting with unilateral facial pain triggered by touching the affected part of the face (typical of trigeminal neuralgia) and who do not respond adequately to medical treatment should be referred for further specialist assessment, which may include surgical options.

Educational content only. Always verify information and use clinical judgement.