Which initial investigations should be performed in a patient suspected of having a subarachnoid haemorrhage?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 16 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Perform a non-contrast CT head scan urgently if a person presents with suspected subarachnoid haemorrhage, especially within 6 hours of symptom onset, as its diagnostic accuracy is highest during this period .

If the CT scan done within 6 hours shows no evidence of haemorrhage, consider a lumbar puncture if the suspicion remains high, ideally after at least 12 hours from symptom onset, to detect xanthochromia (elevated bilirubin) in cerebrospinal fluid .

In cases where the CT scan is performed more than 6 hours after symptom onset and shows no haemorrhage, a lumbar puncture should be considered to confirm or exclude subarachnoid haemorrhage .

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