What are the recommended screening tests for pregnant women during their first antenatal visit?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 16 August 2025Updated: 16 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

During the first antenatal (booking) appointment, the recommended screening tests for pregnant women include:

  • Measurement of height and weight to calculate body mass index (BMI) to assess risk factors such as venous thromboembolism and pre-eclampsia .
  • Blood tests to check full blood count, blood group, and rhesus D status ,.
  • Screening for infectious diseases including HIV, syphilis, and hepatitis B as part of the NHS infectious diseases in pregnancy screening programme ,.
  • Screening for sickle cell and thalassaemia according to the NHS sickle cell and thalassaemia screening programme ,.
  • Discussion and offer of the NHS fetal anomaly screening programme, including the option of an early ultrasound scan between 11+2 and 14+1 weeks for gestational age, multiple pregnancy, and chromosomal abnormalities screening .
  • Blood pressure measurement and urine dipstick testing for proteinuria to assess for hypertension and pre-eclampsia risk ,.
  • Assessment of risk factors for venous thromboembolism (VTE) and gestational diabetes, with referral for further testing or specialist care if indicated ,.
  • Discussion about mental health screening and other social factors such as domestic abuse and female genital mutilation (FGM) ,.

Women should be informed that they have the right to accept or decline any part of the screening programmes offered ,.

Related Knowledge Topics

Educational content only. Always verify information and use clinical judgement.