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What are the key diagnostic criteria for idiopathic pulmonary fibrosis in primary care?

Answer

Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 16 August 2025

Key diagnostic criteria for idiopathic pulmonary fibrosis (IPF) in primary care include:

  • Age over 45 years.
  • Persistent breathlessness on exertion.
  • Persistent cough.
  • Bilateral inspiratory crackles on chest auscultation.
  • Clubbing of the fingers.
  • Spirometry results that are normal or show an impaired restrictive pattern (sometimes obstructive).

Initial assessment should include a detailed history, clinical examination, and blood tests to exclude alternative diagnoses such as environmental/occupational lung diseases, connective tissue diseases, and drug-induced lung disease.

Primary care should also arrange lung function testing (spirometry and gas transfer) and review chest X-ray results.

Referral for high-resolution CT of the thorax and specialist multidisciplinary team assessment is required for definitive diagnosis.

Diagnosis of IPF must be confirmed by a multidisciplinary team based on clinical features, lung function, radiological findings, and pathology if indicated.

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This content was generated by iatroX. Always verify information and use clinical judgment.