Which medications commonly contribute to hyperkalaemia that I should review in my patients?

Medications commonly contributing to hyperkalaemia that should be reviewed in patients include:

• Angiotensin-converting enzyme (ACE) inhibitors
• Angiotensin II receptor blockers (ARBs)
• Aldosterone antagonist potassium-sparing diuretics such as spironolactone and eplerenone
• Potassium-sparing diuretics like amiloride

These medications reduce urinary potassium excretion, increasing the risk of hyperkalaemia, especially in patients with heart failure or chronic kidney disease.

Careful monitoring of serum potassium and renal function is recommended when these drugs are prescribed, particularly in patients with reduced estimated glomerular filtration rate (eGFR).

Other medications such as digoxin and certain diuretics may also influence potassium levels but are less commonly implicated in causing hyperkalaemia directly.