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What are the potential side effects of topical treatments for seborrhoeic dermatitis that I should discuss with my patients?

Answer

Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 16 August 2025

When discussing topical treatments for seborrhoeic dermatitis with patients, it is important to highlight potential side effects, particularly concerning topical corticosteroids 1.

  • Thinning of the skin (skin atrophy): This is a potential adverse effect of topical corticosteroids, especially with prolonged use 1. Strong topical corticosteroid scalp applications are not suitable for application to the beard area due to the risk of skin thinning on the face 1.
  • Striae: Continuous use of potent or very potent corticosteroids may cause irreversible skin atrophy and striae 2.
  • Systemic side effects: These can occur when potent or very potent corticosteroids are applied continuously to extensive areas of the body (e.g., more than 10% of body surface area) 2.

Patients should be advised that topical corticosteroids are generally for short-term use, typically up to 2 weeks for flares, to help settle inflammation 1. For antifungals like ketoconazole, treatment has been shown to have a lower rate of adverse effects compared to steroids [Okokon, 2015].

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This content was generated by iatroX. Always verify information and use clinical judgment.