What are the first-line treatment options for a patient diagnosed with contact dermatitis?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 16 August 2025Updated: 16 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

The first-line treatment options for a patient diagnosed with contact dermatitis primarily involve identifying and avoiding the causative stimulus, alongside supportive skin care and symptomatic relief .

  • Avoidance of the Stimulus: The most crucial element of treatment and prevention is advising the patient to avoid the identified causative agent . Clinical improvement may take 8–12 weeks of avoidance . If complete avoidance is not possible, advise measures to minimise contact, such as rinsing with water or washing with a soap substitute immediately after contact . Overuse of skin-cleaning agents can worsen the condition . Suggest substituting products containing identified allergens or irritants . Recommend using cotton-lined rubber or plastic gloves for handling potential irritants, ensuring gloves are removed frequently to prevent sweating from aggravating dermatitis . Advise avoiding the accumulation of chemicals and water under jewellery .
  • Emollients and Soap Substitutes: Advise the liberal use of emollients and soap substitutes to maintain skin hydration and improve barrier repair . Patients must be warned about the fire risk associated with emollients in contact with dressings, clothing, or bedding, and should avoid smoking or naked flames . Aqueous cream should not be prescribed as it is associated with a high risk of skin reactions .
  • Topical Corticosteroids: Consider the need for topical corticosteroids to control symptoms . The choice of topical corticosteroid depends on the clinical situation, including the patient's age, severity, location, and extent of the dermatitis .

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