What are the recommended guidelines for managing hypertension in primary care?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 16 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

In primary care, the management of hypertension involves a combination of lifestyle interventions and pharmacological treatment, with regular monitoring of blood pressure to achieve target levels .

Offer lifestyle advice periodically, including promoting a healthy diet, regular exercise, weight loss if overweight, and reducing alcohol and caffeine intake .

Encourage low dietary sodium intake, but avoid salt substitutes containing potassium chloride in older people, those with diabetes, pregnant women, and individuals with kidney disease or on certain antihypertensives .

Advise and support smoking cessation and inform about local initiatives supporting healthy lifestyle changes .

For pharmacological treatment, first-line options depend on age, ethnicity, and comorbidities: for those under 55 years and not of black African or African-Caribbean origin, an ACE inhibitor or ARB is recommended; for those aged 55 and over, or of black African or Caribbean origin, a calcium-channel blocker or thiazide-like diuretic is preferred .

When blood pressure remains uncontrolled, stepwise addition of other antihypertensive agents such as CCBs, thiazide-like diuretics, or combination therapy is advised, with titration to the highest tolerated dose .

Monitor response to treatment regularly, aiming for blood pressure below 140/90 mmHg in adults under 80, and below 150/90 mmHg in those aged 80 and over, adjusting for frailty or multimorbidity based on clinical judgment .

Perform investigations for target organ damage, including urine tests, blood tests, fundi examination, and ECG, at diagnosis and during management .

Review blood pressure control and medication adherence periodically, especially when treatment is escalated or changed .

In cases of resistant hypertension, confirm elevated blood pressure with ambulatory or home monitoring, assess adherence, and consider specialist referral for further management .

Educational content only. Always verify information and use clinical judgement.