How should I manage a patient with a corneal abrasion who presents with significant pain and photophobia?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 16 August 2025Updated: 16 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Management of a patient with corneal abrasion presenting with significant pain and photophobia:

  • Perform a thorough eye examination including visual acuity assessment and fluorescein staining to confirm the abrasion and exclude foreign bodies or other complications .
  • Remove any loose superficial foreign bodies if expertise and equipment are available; use topical anaesthetic (one drop of proxymetacaine 0.5%) to aid removal but avoid repeated doses due to toxicity and delayed healing .
  • Advise the patient to avoid touching or rubbing the eye and to avoid contact lens use until healing is complete .
  • Provide symptom relief with simple oral analgesics such as paracetamol; topical analgesics and cycloplegics are not recommended as they do not improve healing or pain and may cause adverse effects .
  • Recommend ocular lubricants (non-prescription lubricating eye drops or ointment) to alleviate discomfort; eye drops may be preferred during the day and ointments at night .
  • Advise wearing sunglasses or staying in low light environments to reduce photophobia and light sensitivity .
  • Consider prescribing a broad-spectrum topical antibiotic such as chloramphenicol if there is a risk of infection, especially if the abrasion is contaminated or associated with foreign matter; continue antibiotics until 24 hours after symptoms resolve .
  • Do not routinely use eye patches as evidence does not support benefit in healing or pain reduction .
  • Arrange follow-up within 24 hours to reassess symptoms and healing; instruct the patient to seek urgent review if symptoms worsen, vision decreases, or signs of infection develop .
  • Refer urgently to ophthalmology if there is significant visual acuity reduction, increasing size of abrasion, corneal infiltrate, ulcer, infection, or if the abrasion does not heal within 3–4 days .

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