What are the recommended treatment options for managing arterial ulcers in a primary care setting?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 16 August 2025Updated: 16 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Treatment options for managing arterial ulcers in a primary care setting include:

  • Urgent referral: Refer patients with arterial ulcers, especially those with chronic limb-threatening ischaemia, urgently to a vascular multidisciplinary team for assessment and management, as revascularisation may be required ,.
  • Pain management: Offer analgesia such as paracetamol and opioids depending on pain severity, with consideration of neuropathic pain treatments if present .
  • Wound care: Maintain cleanliness of the ulcer, avoid strict aseptic technique but prevent cross-infection, and use appropriate dressings that are non-adherent and suited to the wound characteristics; debridement may be considered if necrotic tissue is present but should be done by trained professionals ,.
  • Secondary prevention and risk factor management: Address cardiovascular risk factors including smoking cessation, diabetes control, lipid management, blood pressure control, and encourage exercise to prevent disease progression ,.
  • Patient education: Provide tailored information about the condition, risks, treatment options, foot care, and lifestyle modifications to support shared decision-making and self-care ,.
  • Compression therapy: Generally contraindicated in pure arterial ulcers due to risk of worsening ischaemia; thus, compression should be avoided unless mixed aetiology is confirmed and managed by specialists .

In summary, primary care management focuses on initial wound care, pain control, risk factor modification, patient education, and prompt referral to vascular specialists for further assessment and possible revascularisation ,,.

Educational content only. Always verify information and use clinical judgement.