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How should I approach the referral process for a patient with suspected brain tumour symptoms, including the necessary imaging studies?
Answer
Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 16 August 2025
Referral Process for Suspected Brain Tumour:
- For adults presenting with progressive, sub-acute loss of central neurological function suggestive of a brain tumour, consider an urgent referral for a direct access MRI scan of the brain, or a CT scan if MRI is contraindicated, to be performed within 2 weeks.
- For children and young people with newly abnormal cerebellar or other central neurological function, consider a very urgent referral for specialist assessment, aiming for an appointment within 48 hours.
- If there is uncertainty about symptom interpretation or referral necessity, discuss the case with a specialist (e.g., via telephone or email) to communicate concerns and urgency.
- Ensure referral letters include all relevant clinical information and specify whether the referral is urgent or non-urgent, using local referral proformas if available.
- Make the referral within 1 working day once the decision is made.
Imaging Investigations:
- Offer standard structural MRI (including T2 weighted, FLAIR, DWI series, and T1 pre- and post-contrast volume) as the initial diagnostic test for suspected glioma or brain tumour unless contraindicated.
- If MRI is contraindicated, a CT scan may be used as an alternative.
- Consider advanced MRI techniques such as MR perfusion, diffusion tensor imaging, and MR spectroscopy if standard imaging results are unclear or to assess tumour grade.
- Refer patients with suspected glioma to a specialist multidisciplinary team at first radiological diagnosis for management.
Key References
- CKS - Brain and central nervous system cancers - recognition and referral
- CKS - Central nervous system and brain cancers - recognition and referral
- NG99 - Brain tumours (primary) and brain metastases in over 16s
- CKS - Haematological cancers - recognition and referral
- CKS - Childhood cancers - recognition and referral
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