What are the indications for prescribing an adrenaline auto-injector to patients with a history of anaphylaxis?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 16 August 2025Updated: 16 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

The indications for prescribing an adrenaline auto-injector to patients with a history of anaphylaxis include having experienced a suspected anaphylactic reaction, which is characterized by rapidly developing, life-threatening problems involving the airway, breathing, and/or circulation, often with skin and mucosal changes .

After emergency treatment for suspected anaphylaxis, an appropriate adrenaline injector should be offered as an interim measure before a specialist allergy service appointment, with a prescription for 2 further adrenaline injectors, and advice to carry them at all times .

Patients should be provided with information on the signs and symptoms of anaphylaxis, the risk of biphasic reactions, and instructions on when to use the adrenaline auto-injector, including demonstrating correct use .

Educational content only. Always verify information and use clinical judgement.