What lifestyle modifications should I recommend to patients with essential thrombocythaemia to reduce their risk of complications?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 16 August 2025Updated: 16 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Lifestyle modifications for patients with essential thrombocythaemia to reduce their risk of complications include:

  • Targeted management of cardiovascular risk factors: Advise patients to control hypertension, hypercholesterolaemia, diabetes mellitus, and to stop smoking, as these factors increase thrombotic risk.
  • Healthy diet: Recommend a cardioprotective diet with total fat intake less than 30% of total energy, saturated fats less than 7%, and replacement of saturated fats with mono- and polyunsaturated fats such as olive or rapeseed oil.
  • Physical activity: Encourage regular aerobic and muscle-strengthening activities according to UK Chief Medical Officers' guidelines, tailored to the patient's capacity and comorbidities.
  • Patient education and support: Provide information about the condition, risks, and importance of lifestyle changes to empower self-management.

These lifestyle measures complement pharmacological treatments and monitoring to reduce thrombosis and bleeding risks in essential thrombocythaemia.

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