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What are the recommended vaccination protocols for patients with a history of COVID-19 infection?

Answer

Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 14 August 2025

For patients with a history of COVID-19 infection, vaccination protocols recommend deferring immunisation if they are acutely unwell until they have fully recovered 1. This helps avoid wrongly attributing symptoms of acute illness to vaccine adverse effects 1. If a patient has suspected COVID-19 infection, they should not attend for vaccination to prevent infecting others 1.

Ideally, for adults and children at highest risk of serious illness, vaccination should be deferred until clinical recovery and at least 4 weeks after the onset of symptoms or 4 weeks from the first positive PCR result, based on clinical judgement 1. It is important to note that prolonged symptoms of COVID-19 are not a contraindication to the COVID-19 vaccine 1. However, if there is evidence of current deterioration, vaccination may be deferred to avoid incorrectly attributing any change in the patient’s underlying condition to the vaccine 1.

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This content was generated by iatroX. Always verify information and use clinical judgment.