What non-pharmacological interventions are effective for managing mild to moderate depression in primary care?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 14 August 2025Updated: 14 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Effective non-pharmacological interventions for managing mild to moderate depression in primary care include individual guided self-help programmes based on the principles of CBT, which involve behavioural activation and problem-solving techniques, supported by a trained practitioner, and typically delivered over 9 to 12 weeks with up to 6 to 8 sessions (face-to-face and via telephone) .

Computer-based or web-based cognitive behavioural therapy (CBT) programmes are also recommended, which include explanations of the CBT model, encourage tasks between sessions, and involve limited facilitation by a trained practitioner, usually over 9 to 12 weeks .

Sleep hygiene advice, such as establishing regular sleep and wake times, avoiding excess eating, smoking, or alcohol before sleep, creating a proper sleep environment, and engaging in regular physical activity, is advised for patients with depression .

Active monitoring, including discussing the presenting problem, providing information about depression, arranging further assessment within 2 weeks, and making contact if follow-up is missed, is recommended for patients with mild depression who do not want formal intervention or are recovering .

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