A 73-year-old man with a history of recurrent C. difficile infection presents with a fourth episode. He has been on prolonged courses of broad-spectru...

Question

A 73-year-old man with a history of recurrent C. difficile infection presents with a fourth episode. He has been on prolonged courses of broad-spectrum antibiotics for recurrent UTIs. He has CKD stage 3a. What is the MOST important strategy to prevent further C. difficile recurrence?

Accepted Answer

Implement antimicrobial stewardship - reduce unnecessary and broad-spectrum antibiotic use, and consider Fidaxomicin for the current episode

Answer

Prescribe prophylactic Metronidazole indefinitely

Answer

Start long-term proton pump inhibitor therapy

Answer

Prescribe prophylactic Ciprofloxacin for UTIs

Answer

Administer faecal microbiota transplantation as first-line

uk-dgm MCQ (SBA): C. difficile Prevention and Antimicrobial Stewardship

A 73-year-old man with a history of recurrent C. difficile infection presents with a fourth episode. He has been on prolonged courses of broad-spectrum antibiotics for recurrent UTIs. He has CKD stage 3a. What is the MOST important strategy to prevent further C. difficile recurrence?