A 26-year-old woman presents to the GP with primary amenorrhoea. She has well-developed breasts but no pubic or axillary hair. Pelvic examination reve...

Question

A 26-year-old woman presents to the GP with primary amenorrhoea. She has well-developed breasts but no pubic or axillary hair. Pelvic examination reveals a short, blind-ending vagina. Karyotype is 46,XY. What is the most likely diagnosis?

Accepted Answer

Complete androgen insensitivity syndrome

Answer

Turner syndrome

Answer

Müllerian agenesis (Mayer-Rokitansky-Küster-Hauser syndrome)

Answer

Congenital adrenal hyperplasia

Answer

Kallmann syndrome

uk-drcog MCQ (SBA): Complete Androgen Insensitivity Syndrome

A 26-year-old woman presents to the GP with primary amenorrhoea. She has well-developed breasts but no pubic or axillary hair. Pelvic examination reveals a short, blind-ending vagina. Karyotype is 46,XY. What is the most likely diagnosis?