A 32-year-old woman presents with intermittent diarrhoea, abdominal bloating and weight loss. She has iron deficiency anaemia. Tissue transglutaminase...

Question

A 32-year-old woman presents with intermittent diarrhoea, abdominal bloating and weight loss. She has iron deficiency anaemia. Tissue transglutaminase (tTG) IgA antibodies are strongly positive. What is the most appropriate next diagnostic step?

Accepted Answer

Arrange upper GI endoscopy with duodenal biopsies

Answer

Start a gluten-free diet immediately with no further investigation

Answer

Order CT abdomen

Answer

Arrange colonoscopy only

Answer

Check Helicobacter pylori status

uk-plab-1 MCQ (SBA): Coeliac disease

A 32-year-old woman presents with intermittent diarrhoea, abdominal bloating and weight loss. She has iron deficiency anaemia. Tissue transglutaminase (tTG) IgA antibodies are strongly positive. What is the most appropriate next diagnostic step?