A 40-year-old man presents with a 3-month history of watery diarrhoea, weight loss and lethargy. Tissue transglutaminase IgA antibodies are strongly p...

Question

A 40-year-old man presents with a 3-month history of watery diarrhoea, weight loss and lethargy. Tissue transglutaminase IgA antibodies are strongly positive. What is the most appropriate next step in management?

Accepted Answer

Arrange duodenal biopsy via endoscopy while the patient continues to eat gluten

Answer

Advise starting a strict gluten-free diet immediately without further tests

Answer

Reassure and repeat antibodies in 1 year

Answer

Start steroids for presumed inflammatory bowel disease

Answer

Advise lactose-free diet only

uk-plab-1 MCQ (SBA): Coeliac disease

A 40-year-old man presents with a 3-month history of watery diarrhoea, weight loss and lethargy. Tissue transglutaminase IgA antibodies are strongly positive. What is the most appropriate next step in management?