A 48-year-old man with a history of gout controlled on allopurinol is starting a thiazide diuretic for hypertension. What should you consider regardin...

Question

A 48-year-old man with a history of gout controlled on allopurinol is starting a thiazide diuretic for hypertension. What should you consider regarding his gout management?

Accepted Answer

Monitor serum urate and gout symptoms because thiazides may increase urate levels and adjust allopurinol if needed

Answer

Stop allopurinol because thiazides will control urate

Answer

Start long-term NSAIDs for prophylaxis only

Answer

Switch to loop diuretics solely to avoid gout

Answer

There is no interaction and no monitoring is needed

uk-plab-1 MCQ (SBA): Gout and thiazide diuretics

A 48-year-old man with a history of gout controlled on allopurinol is starting a thiazide diuretic for hypertension. What should you consider regarding his gout management?