A 60-year-old man with known diabetic nephropathy and hypertension has a urine albumin:creatinine ratio (ACR) of 45 mg/mmol and eGFR 50 mL/min/1.73 m²...

Question

A 60-year-old man with known diabetic nephropathy and hypertension has a urine albumin:creatinine ratio (ACR) of 45 mg/mmol and eGFR 50 mL/min/1.73 m². His blood pressure is 145/90 mmHg on Amlodipine alone. What is the most appropriate change to his antihypertensive therapy?

Accepted Answer

Add an ACE inhibitor such as Ramipril

Answer

Continue Amlodipine alone

Answer

Add a thiazide diuretic only

Answer

Switch to a beta blocker alone

Answer

Withhold all antihypertensives to protect renal function

uk-plab-1 MCQ (SBA): CKD with albuminuria – ACE inhibitor use

A 60-year-old man with known diabetic nephropathy and hypertension has a urine albumin:creatinine ratio (ACR) of 45 mg/mmol and eGFR 50 mL/min/1.73 m². His blood pressure is 145/90 mmHg on Amlodipine alone. What is the most appropriate change to his antihypertensive therapy?