A 50-year-old man presents with burning epigastric discomfort and regurgitation, especially when lying down at night. Endoscopy shows Los Angeles grad...

Question

A 50-year-old man presents with burning epigastric discomfort and regurgitation, especially when lying down at night. Endoscopy shows Los Angeles grade B oesophagitis. Lifestyle measures have not relieved symptoms. What is the most appropriate pharmacological management?

Accepted Answer

Standard-dose proton pump inhibitor once daily for at least 4-8 weeks

Answer

Antacids as sole therapy

Answer

H2 receptor antagonist at night only

Answer

Prokinetic agent alone

Answer

Immediate referral for anti-reflux surgery

au-amc MCQ (SBA): Gastro-oesophageal reflux disease

A 50-year-old man presents with burning epigastric discomfort and regurgitation, especially when lying down at night. Endoscopy shows Los Angeles grade B oesophagitis. Lifestyle measures have not relieved symptoms. What is the most appropriate pharmacological management?