A 37-year-old woman presents with fatigue, weight gain, cold intolerance, and constipation for 6 months. TSH is 12 mIU/L (normal 0.4-4.0) and free T4 ...

Question

A 37-year-old woman presents with fatigue, weight gain, cold intolerance, and constipation for 6 months. TSH is 12 mIU/L (normal 0.4-4.0) and free T4 is at the lower limit of normal. Thyroid peroxidase antibodies are positive. According to Canadian and international guidance, what is the most appropriate management?

Accepted Answer

Start levothyroxine replacement therapy

Answer

Observe without treatment and repeat thyroid function tests in 12 months

Answer

Start antithyroid drugs

Answer

Start iodine supplementation only

Answer

Refer for urgent thyroid surgery

ca-mccqe1 MCQ (SBA): Subclinical hypothyroidism - treatment