A 45-year-old woman is diagnosed with seropositive rheumatoid arthritis affecting hands and wrists with morning stiffness of 2 hours. According to Can...

Question

A 45-year-old woman is diagnosed with seropositive rheumatoid arthritis affecting hands and wrists with morning stiffness of 2 hours. According to Canadian rheumatology guidance, which is the most appropriate initial disease-modifying therapy?

Accepted Answer

Methotrexate as first-line DMARD

Answer

Hydroxychloroquine monotherapy in all patients

Answer

Non-steroidal anti-inflammatory drugs alone

Answer

Long-term oral prednisone monotherapy

Answer

Biologic therapy as first-line in all patients

ca-mccqe1 MCQ (SBA): Rheumatoid arthritis - first-line DMARD

A 45-year-old woman is diagnosed with seropositive rheumatoid arthritis affecting hands and wrists with morning stiffness of 2 hours. According to Canadian rheumatology guidance, which is the most appropriate initial disease-modifying therapy?