A 48-year-old overweight man has recurrent epigastric pain relieved by food. Endoscopy confirms duodenal ulcer and H. pylori infection. He smokes 10 c...

Question

A 48-year-old overweight man has recurrent epigastric pain relieved by food. Endoscopy confirms duodenal ulcer and H. pylori infection. He smokes 10 cigarettes per day. After standard triple therapy, his stool antigen remains positive. What is the most appropriate next step?

Accepted Answer

Switch to a bismuth-containing or alternative regimen guided by local resistance and specialist advice

Answer

Repeat the same triple therapy regimen immediately

Answer

No further treatment is required if symptoms have settled

Answer

Start lifelong proton pump inhibitor alone

Answer

Perform annual endoscopies only

au-racp MCQ (SBA): Helicobacter pylori eradication failure

A 48-year-old overweight man has recurrent epigastric pain relieved by food. Endoscopy confirms duodenal ulcer and H. pylori infection. He smokes 10 cigarettes per day. After standard triple therapy, his stool antigen remains positive. What is the most appropriate next step?