A 45-year-old man presents with a 3-month history of low mood, anhedonia, poor sleep, and impaired concentration. He denies suicidal ideation. There i...

Question

A 45-year-old man presents with a 3-month history of low mood, anhedonia, poor sleep, and impaired concentration. He denies suicidal ideation. There is no history of mania or psychosis, and no substance misuse. According to CANMAT guidelines, what is an appropriate first-line treatment option for moderate major depressive disorder?

Accepted Answer

Cognitive behavioural therapy or an SSRI as monotherapy

Answer

Tricyclic antidepressant plus antipsychotic

Answer

Benzodiazepine monotherapy

Answer

Electroconvulsive therapy as first-line in all cases

Answer

St Johns wort without medical supervision

ca-mccqe1 MCQ (SBA): Major depressive disorder