A 58-year-old woman presents with progressive numbness and tingling in her hands and feet, unsteady gait and glossitis. She follows a strict vegan die...

Question

A 58-year-old woman presents with progressive numbness and tingling in her hands and feet, unsteady gait and glossitis. She follows a strict vegan diet. Laboratory tests show macrocytic anaemia and low vitamin B12 level. What is the most appropriate treatment?

Accepted Answer

Intramuscular vitamin B12 replacement, followed by lifelong maintenance therapy.

Answer

Oral folic acid alone.

Answer

High-dose oral iron supplementation.

Answer

No treatment; observe only.

Answer

Plasmapheresis.

ca-mccqe1 MCQ (SBA): Vitamin B12 deficiency

A 58-year-old woman presents with progressive numbness and tingling in her hands and feet, unsteady gait and glossitis. She follows a strict vegan diet. Laboratory tests show macrocytic anaemia and low vitamin B12 level. What is the most appropriate treatment?