A 29 year old woman with extensive colonic Crohn disease has been treated with azathioprine and intermittent steroids but continues to have frequent f...

Question

A 29 year old woman with extensive colonic Crohn disease has been treated with azathioprine and intermittent steroids but continues to have frequent flares and steroid dependence. Which next line therapy is most appropriate?

Accepted Answer

Commence anti TNF biologic therapy such as infliximab

Answer

Long term high dose prednisolone

Answer

Switch to 5 ASA therapy alone

Answer

No further therapy; Crohn disease is self limiting

Answer

Total parenteral nutrition as sole treatment

au-racp MCQ (SBA): Complex IBD biologic therapy escalation

A 29 year old woman with extensive colonic Crohn disease has been treated with azathioprine and intermittent steroids but continues to have frequent flares and steroid dependence. Which next line therapy is most appropriate?