A 24-year-old man presents to a remote clinic with painless genital ulceration and a generalised maculopapular rash on the trunk and palms. He has had...

Question

A 24-year-old man presents to a remote clinic with painless genital ulceration and a generalised maculopapular rash on the trunk and palms. He has had multiple sexual partners and inconsistent condom use. Which single investigation is most appropriate to confirm the presumptive diagnosis?

Accepted Answer

Non-treponemal test (RPR or VDRL) and treponemal-specific serology

Answer

First void urine NAAT for chlamydia

Answer

Serum HIV antigen/antibody test only

Answer

Urethral swab culture only

Answer

No testing; treat empirically

au-amc MCQ (SBA): Secondary syphilis

A 24-year-old man presents to a remote clinic with painless genital ulceration and a generalised maculopapular rash on the trunk and palms. He has had multiple sexual partners and inconsistent condom use. Which single investigation is most appropriate to confirm the presumptive diagnosis?