A 55-year-old man with BMI 34 kg/m² is found to have elevated ALT and ultrasound features of hepatic steatosis. Viral hepatitis serology is negative a...

Question

A 55-year-old man with BMI 34 kg/m² is found to have elevated ALT and ultrasound features of hepatic steatosis. Viral hepatitis serology is negative and there is no significant alcohol intake. What is the cornerstone of his management?

Accepted Answer

Weight loss through diet and exercise with management of metabolic risk factors

Answer

Immediate liver biopsy and high-dose steroids

Answer

Start long-term prophylactic antibiotics

Answer

Begin routine surveillance for hepatocellular carcinoma every 6 months

Answer

Start high-dose vitamin E without lifestyle change

au-racgp MCQ (SBA): Non-alcoholic fatty liver disease

A 55-year-old man with BMI 34 kg/m² is found to have elevated ALT and ultrasound features of hepatic steatosis. Viral hepatitis serology is negative and there is no significant alcohol intake. What is the cornerstone of his management?