A 45-year-old woman presents with fever, flank pain and nausea. She is tachycardic, has right costovertebral angle tenderness and no features of sepsi...

Question

A 45-year-old woman presents with fever, flank pain and nausea. She is tachycardic, has right costovertebral angle tenderness and no features of sepsis-induced organ dysfunction. She can tolerate oral intake. What is the most appropriate empirical antibiotic strategy for presumed acute pyelonephritis managed as an inpatient?

Accepted Answer

Intravenous ceftriaxone followed by oral step-down based on culture

Answer

Oral trimethoprim alone for 3 days

Answer

Oral nitrofurantoin for 7 days

Answer

Intravenous benzylpenicillin alone

Answer

No antibiotics until imaging is completed

au-amc MCQ (SBA): Acute pyelonephritis