A 29-year-old man with known ulcerative colitis limited to the distal colon presents with increased bloody diarrhoea and abdominal cramps. He is afebr...

Question

A 29-year-old man with known ulcerative colitis limited to the distal colon presents with increased bloody diarrhoea and abdominal cramps. He is afebrile, with normal haemoglobin and inflammatory markers mildly elevated. What is the most appropriate first-line therapy for this mild to moderate flare?

Accepted Answer

Topical rectal mesalazine with or without oral mesalazine

Answer

Oral mesalazine alone

Answer

High-dose systemic corticosteroids only

Answer

Start biologic therapy immediately

Answer

No treatment is required

au-amc MCQ (SBA): Ulcerative colitis flare