A 72-year-old man presents with acute kidney injury. He was started on high-dose ibuprofen for osteoarthritis 1 week ago. His serum creatinine has ris...

Question

A 72-year-old man presents with acute kidney injury. He was started on high-dose ibuprofen for osteoarthritis 1 week ago. His serum creatinine has risen from 90 to 220 micromol/L. He is mildly dehydrated, and urinalysis shows bland sediment. What is the most likely cause of his AKI?

Accepted Answer

Pre-renal azotaemia due to NSAID-associated reduced renal perfusion

Answer

Intrinsic acute tubular necrosis from aminoglycoside toxicity

Answer

Acute interstitial nephritis due to penicillin

Answer

Post-renal obstruction due to prostatic enlargement

Answer

Rapidly progressive glomerulonephritis

au-amc MCQ (SBA): NSAID-associated AKI

A 72-year-old man presents with acute kidney injury. He was started on high-dose ibuprofen for osteoarthritis 1 week ago. His serum creatinine has risen from 90 to 220 micromol/L. He is mildly dehydrated, and urinalysis shows bland sediment. What is the most likely cause of his AKI?