A 62-year-old woman with recurrent gout on allopurinol 300 mg/day has urate 5.2 mg/dL but frequent flares. Best adjunct to reduce flare frequency duri...

Question

A 62-year-old woman with recurrent gout on allopurinol 300 mg/day has urate 5.2 mg/dL but frequent flares. Best adjunct to reduce flare frequency during ULT titration?

Accepted Answer

Colchicine prophylaxis 0.6 mg once or twice daily

Answer

Stop ULT

Answer

High-dose ibuprofen daily for months

Answer

Prednisone 10 mg daily chronically

Answer

No prophylaxis needed

us-abfm MCQ (SBA): Gout Flare Prophylaxis

A 62-year-old woman with recurrent gout on allopurinol 300 mg/day has urate 5.2 mg/dL but frequent flares. Best adjunct to reduce flare frequency during ULT titration?