A 67-year-old hospitalized patient develops watery diarrhea after antibiotics. Initial nonfulminant C. difficile infection is confirmed by NAAT. Best ...

Question

A 67-year-old hospitalized patient develops watery diarrhea after antibiotics. Initial nonfulminant C. difficile infection is confirmed by NAAT. Best initial therapy?

Accepted Answer

Fidaxomicin 200 mg PO twice daily for 10 days

Answer

Metronidazole 500 mg PO three times daily for 10 days

Answer

Vancomycin 125 mg PO four times daily for 3 days then stop if improved

Answer

Probiotics only

Answer

Tigecycline IV

us-abfm MCQ (SBA): Clostridioides difficile Infection

A 67-year-old hospitalized patient develops watery diarrhea after antibiotics. Initial nonfulminant C. difficile infection is confirmed by NAAT. Best initial therapy?