A 28-year-old at 38 weeks gestation, with no history of penicillin allergy, has unknown Group B Streptococcus (GBS) status and presents in labor with ...

Question

A 28-year-old at 38 weeks gestation, with no history of penicillin allergy, has unknown Group B Streptococcus (GBS) status and presents in labor with rupture of membranes. What intrapartum antibiotic prophylaxis is recommended?

Accepted Answer

Penicillin G 5 million units IV loading, then 2.5-3.0 million units IV every 4 hours until delivery

Answer

Ampicillin 1 g IV every 4 hours

Answer

Vancomycin 1 g IV every 12 hours

Answer

Clindamycin 900 mg IV every 8 hours (no susceptibility data)

Answer

Cefazolin 500 mg IV every 8 hours

us-abfm MCQ (SBA): GBS Prophylaxis

A 28-year-old at 38 weeks gestation, with no history of penicillin allergy, has unknown Group B Streptococcus (GBS) status and presents in labor with rupture of membranes. What intrapartum antibiotic prophylaxis is recommended?