A 35-year-old with severe cellulitis (no abscess) and fever receives vancomycin. When should broad Gram-negative/anaerobic coverage be added?...

Question

A 35-year-old with severe cellulitis (no abscess) and fever receives vancomycin. When should broad Gram-negative/anaerobic coverage be added?

Accepted Answer

If WBC >12,000

Answer

Never indicated for cellulitis

Answer

If neutropenic, immunocompromised, or severe limb-threatening infection

Answer

Only if MRSA nasal swab positive

Answer

Routinely with vancomycin

us-abem MCQ (SBA): Cellulitis-Antibiotic Spectrum