A 64-year-old with recurrent diverticulitis receives ciprofloxacin/ metronidazole and develops diarrhea; stool toxin positive for C. difficile. He had...

Question

A 64-year-old with recurrent diverticulitis receives ciprofloxacin/ metronidazole and develops diarrhea; stool toxin positive for C. difficile. He had CDI 4 months ago. Best therapy now?

Accepted Answer

Stop antibiotics and observe only

Answer

Metronidazole 500 mg TID x10 days

Answer

Oral vancomycin taper/pulse regimen

Answer

Fecal microbiota transplantation as first-line for recurrence

Answer

Probiotics plus loperamide

us-abim MCQ (SBA): C. difficile (First Recurrence)

A 64-year-old with recurrent diverticulitis receives ciprofloxacin/ metronidazole and develops diarrhea; stool toxin positive for C. difficile. He had CDI 4 months ago. Best therapy now?