A 70-year-old with diabetes and CKD stage 3 returns after initiating SGLT2 inhibitor with dizziness and BP 98/62. Creatinine rose from 1.1 to 1.3 mg/d...

Question

A 70-year-old with diabetes and CKD stage 3 returns after initiating SGLT2 inhibitor with dizziness and BP 98/62. Creatinine rose from 1.1 to 1.3 mg/dL (eGFR drop 10%). What is appropriate?

Accepted Answer

Continue SGLT2 inhibitor with monitoring; small eGFR dip is expected

Answer

Stop immediately; any creatinine rise is harmful

Answer

Double ACE inhibitor dose now

Answer

Start NSAID for BP

Answer

Switch to TZD

us-abim MCQ (SBA): SGLT2 Early eGFR Dip

A 70-year-old with diabetes and CKD stage 3 returns after initiating SGLT2 inhibitor with dizziness and BP 98/62. Creatinine rose from 1.1 to 1.3 mg/dL (eGFR drop 10%). What is appropriate?