A 49-year-old with BMI 34 and A1c 6.1% (prediabetes) asks about diabetes prevention. Which intervention has the strongest evidence for preventing prog...

Question

A 49-year-old with BMI 34 and A1c 6.1% (prediabetes) asks about diabetes prevention. Which intervention has the strongest evidence for preventing progression?

Accepted Answer

Intensive lifestyle intervention (7% weight loss, ≥150 min/week activity)

Answer

Metformin for all patients

Answer

GLP‑1 RA for all with BMI >30

Answer

SGLT2 inhibitor

Answer

No intervention until A1c ≥6.5%

us-abfm MCQ (SBA): Prediabetes-Prevention

A 49-year-old with BMI 34 and A1c 6.1% (prediabetes) asks about diabetes prevention. Which intervention has the strongest evidence for preventing progression?