A 29-year-old with painless genital ulcer, RPR positive. No penicillin allergy, not pregnant. First-line therapy for primary syphilis?...

Question

A 29-year-old with painless genital ulcer, RPR positive. No penicillin allergy, not pregnant. First-line therapy for primary syphilis?

Accepted Answer

Benzathine penicillin G 2.4 million units IM x1

Answer

Penicillin VK 500 mg qid x10 days

Answer

Doxycycline 100 mg bid x7 days

Answer

Ceftriaxone 250 mg IM x1

Answer

No treatment; repeat serology in 3 months

us-abfm MCQ (SBA): Syphilis