A 50-year-old with severe penicillin allergy and GBS colonisation at 36 weeks. Sensitivities show clindamycin-resistant isolate. Best intrapartum prop...

Question

A 50-year-old with severe penicillin allergy and GBS colonisation at 36 weeks. Sensitivities show clindamycin-resistant isolate. Best intrapartum prophylaxis?

Accepted Answer

Vancomycin 20 mg/kg IV every 8-12 hours (max 2 g/dose)

Answer

Clindamycin 900 mg IV every 8 hours

Answer

Penicillin G dosing despite allergy

Answer

No prophylaxis

Answer

Ampicillin 2 g IV then 1 g q4h

us-usmle-step-2 MCQ (SBA): GBS Prophylaxis (Allergy)

A 50-year-old with severe penicillin allergy and GBS colonisation at 36 weeks. Sensitivities show clindamycin-resistant isolate. Best intrapartum prophylaxis?