A 78-year-old man on warfarin for atrial fibrillation presents with sudden-onset headache and vomiting. CT head shows a large intracerebral hemorrhage...

Question

A 78-year-old man on warfarin for atrial fibrillation presents with sudden-onset headache and vomiting. CT head shows a large intracerebral hemorrhage. His INR is 3.5. What is the most appropriate immediate strategy to reverse anticoagulation?

Accepted Answer

Administer prothrombin complex concentrate (PCC) plus IV vitamin K.

Answer

Administer vitamin K 5 mg orally only.

Answer

Stop warfarin and observe without reversal.

Answer

Administer fresh frozen plasma alone.

Answer

Switch from warfarin to a direct oral anticoagulant.

us-abfm MCQ (SBA): Warfarin-Associated Intracerebral Hemorrhage

A 78-year-old man on warfarin for atrial fibrillation presents with sudden-onset headache and vomiting. CT head shows a large intracerebral hemorrhage. His INR is 3.5. What is the most appropriate immediate strategy to reverse anticoagulation?