A 54-year-old man with acute myeloid leukemia receiving induction chemotherapy presents with fever of 102.4°F (39.1°C) and chills. He is hemodynamical...

Question

A 54-year-old man with acute myeloid leukemia receiving induction chemotherapy presents with fever of 102.4°F (39.1°C) and chills. He is hemodynamically stable but profoundly neutropenic with an absolute neutrophil count of 200/µL. What is the most appropriate initial empiric antibiotic regimen?

Accepted Answer

IV cefepime monotherapy.

Answer

Oral amoxicillin-clavulanate.

Answer

IV vancomycin alone.

Answer

Oral ciprofloxacin plus metronidazole.

Answer

No antibiotics until a source is identified.

us-abfm MCQ (SBA): Febrile Neutropenia

A 54-year-old man with acute myeloid leukemia receiving induction chemotherapy presents with fever of 102.4°F (39.1°C) and chills. He is hemodynamically stable but profoundly neutropenic with an absolute neutrophil count of 200/µL. What is the most appropriate initial empiric antibiotic regimen?