A 55-year-old with recurrent gout (≥3 flares/year), SU 9.2 mg/dL, and CKD stage 3 is not on urate-lowering therapy. Which strategy aligns with guideli...

Question

A 55-year-old with recurrent gout (≥3 flares/year), SU 9.2 mg/dL, and CKD stage 3 is not on urate-lowering therapy. Which strategy aligns with guidelines?

Accepted Answer

Start allopurinol at low dose (≤100 mg/day; lower in CKD) with titration to SU

Answer

Febuxostat at high fixed dose without titration

Answer

Probenecid as first-line in CKD stage 3

Answer

Delay ULT until flares stop for 12 months

Answer

Treat flares only; no ULT needed

us-abim MCQ (SBA): Gout-ULT Strategy

A 55-year-old with recurrent gout (≥3 flares/year), SU 9.2 mg/dL, and CKD stage 3 is not on urate-lowering therapy. Which strategy aligns with guidelines?